CDD-1349

• Description:

  CDD-1349 (Compound 15) is a BRDT-BD2/BRD4-BD2 selective inhibitor. CDD-1349is an analog with sixfold selectivity for BRDT-BD2 versus BRD4-BD2. CDD-1349 has an IC50 of 22 nM against BRDT. CDD-1349 can be studied in research on nonhormonal contraceptive agent[1].

• UNSPSC:

  12352005

• Target:

  Epigenetic Reader Domain

• Related Pathways:

  Epigenetics

• Field of Research:

  Endocrinology

• Smiles:

  O=C(C1=CC=C(C(NC)=O)C=C1)NC2=CC(NC(C3=CC(C(C4=C(C)C=C(N)N=C4)=NN5C)=C5C=C3)=O)=CC=C2C

• Molecular Formula:

  C31H29N7O3

• Molecular Weight:

  547.61

• References & Citations:

  [1]Yu, Z., et al., (2021) . Discovery and characterization of bromodomain 2-specific inhibitors of BRDT. Proceedings of the National Academy of Sciences of the United States of America, 118 (9), e2021102118.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2757619-90-0]