BChE-IN-40

• Description :

  BChE-IN-40 (compound D40) is a potent butyrylcholinesterase inhibitor with an IC50 of 0.59 μM. BChE-IN-40 exhibits strong anti-inflammatory effects with an IC50 of 4.55 μM for nitric oxide suppression. BChE-IN-40 demonstrates excellent blood-brain barrier permeability[1].

• UNSPSC :

  12352005

• Target :

  Cholinesterase (ChE)

• Related Pathways :

  Neuronal Signaling

• Field of Research :

  Neurological Disease

• Smiles :

  O=C1C(OCC2=CC=CC=C2)=C(/C=C/C3=CC=C(OC(N(CC)C)=O)C(OC(N(CC)C)=O)=C3)OC=C1

• Molecular Formula :

  C28H30N2O7

• Molecular Weight :

  506.55

• References & Citations :

  [1]Liu X, et al. A novel carbamate-based hybrid derivative with anti-neuroinflammatory properties as a selective butyrylcholinesterase inhibitor for Alzheimer's disease therapy. Bioorg Chem. 2025 Jul 1;161:108551.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported