OZO-Cl

• Description :

  OZO-Cl is an OZO derivative. OZO-Cl has anti-cancer activity. OZO-Cl significantly decreases the intracellular glutathion S-transferase Pi (GST) activity. OZO-Cl exhibits cytotoxicity to cancer cell lines, with IC50s of 150 and 120 μmol/L in Panc-1 and K562 cells respectively[1].

• UNSPSC :

  12352101

• Target :

  Glutathione S-transferase

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Cancer

• Smiles :

  [O-]C1=C(C2=CC=C(Cl)C=C2)[S+]=NO1

• Molecular Formula :

  C8H4ClNO2S

• Molecular Weight :

  213.64

• References & Citations :

  [1]Cui, H., et al., (2008) . 4-Aryl-1,3,2-oxathiazolylium-5-olate: a novel GST inhibitor to release JNK and activate c-Jun for cancer therapy. Cancer chemotherapy and pharmacology, 62 (3), 509–515.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2201798-21-0]