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CL-242817

CAT: 0804-HY-129213Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-129213Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CL-242817 is an orally available angiotensin converting enzyme (ACE) inhibitor. CL-242817 inhibits the conversion of angiotensin I to angiotensin II and has blood pressure lowering activity. CL-242817 can also improve Monocrotaline induced lung injury. CL-242817 can be used in the study of pulmonary fibrosis and hypertension-related diseases[1].
CAS Number
86709-48-0
UNSPSC
12352005
Target
Angiotensin-converting Enzyme (ACE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease; Others
Assay Protocol
https://www.medchemexpress.com/cl-242817.html
Smiles
O=C([C@H]1N(CCC1)C([C@H]([C@@H](C(C2=CC=CC=C2)=O)SC(C)=O)C)=O)O
Molecular Formula
C18H21NO5S
Molecular Weight
363.43
References & Citations
[1]Molteni, et al. Monocrotaline-induced cardiopulmonary damage in rats: amelioration by the angiotensin-converting enzyme inhibitor CL242817. Proceedings of the Society for Experimental Biology and Medicine 182.4 (1986) : 483-493.|[2]FM Lai, et al. Some in vitro and in vivo studies of a new angiotensin I‐converting enzyme inhibitor [[S‐ (R*), S*]‐1‐[ (3‐acetylthio) ‐3‐benzoyl‐2‐methylpropionyl]‐L‐proline] (CL 242,817) in comparison with captopril. Drug Development Research 3.3 (1983) : 261-269.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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