OZO-H

• Description :

  OZO-H is a GST inhibitor. OZO-H is an OZO derivative with potent anti-cancer effects. OZO-H releases JNK1 from GST-JNK1 complex. OZO-H induces JNK1 phosphorylation and activates c-Jun in cancer cells[1].

• Product Name Alternative :

  CAY10562

• UNSPSC :

  12352005

• Target :

  Glutathione S-transferase; JNK

• Related Pathways :

  MAPK/ERK Pathway; Metabolic Enzyme/Protease

• Field of Research :

  Cancer

• Smiles :

  [O-]C1=C(C2=CC=CC=C2)SN=[O+]1

• Molecular Formula :

  C8H5NO2S

• Molecular Weight :

  179.20

• References & Citations :

  [1]Cui, H., et al., (2008) . 4-Aryl-1,3,2-oxathiazolylium-5-olate: a novel GST inhibitor to release JNK and activate c-Jun for cancer therapy. Cancer chemotherapy and pharmacology, 62 (3), 509–515.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [60027-35-2]