PSMA-DIM

• Description :

  PSMA-DIM is a dimeric PSMA ligand with a Kd of 37.09 nM for LNCaP cells. PSMA-DIM can be radiolabeled with [68Ga]Ga to form [68Ga]Ga-PSMA-DIM. [68Ga]Ga-PSMA-DIM can effectively distinguish between cells and animal models with different expression levels of PSMA. [68Ga]Ga-PSMA-DIM exhibits high LNCaP cells uptake and tumor uptake peak values. PSMA-DIM can be used for the study of prostate cancer (PCa) [1].

• UNSPSC :

  12352211

• Target :

  PSMA

• Related Pathways :

  Immunology/Inflammation

• Field of Research :

  Cancer

• Smiles :

  IC1=CC=C(C=C1)CCCC(NCCCCC(C(NC(CCC(NCCOCCOCCOCCOCC(NC2CCN(C(N[C@H](C(NCCCC[C@@H](C(O)=O)NC(N[C@@H](CCC(O)=O)C(O)=O)=O)=O)CC3=CC=C4C=CC=CC4=C3)=O)CC2)=O)=O)C(NCCOCCOCCOCCOCC(NC5CCN(C(N[C@H](C(NCCCC[C@@H](C(O)=O)NC(N[C@@H](CCC(O)=O)C(O)=O)=O)=O)CC6=CC=C7C=CC=CC7=C6)=O)CC5)=O)=O)=O)NC(CN8CCN(CCN(CCN(CC8)CC(O)=O)CC(O)=O)CC(O)=O)=O)=O

• Molecular Formula :

  C119H174IN21O39

• Molecular Weight :

  2649.68

• References & Citations :

  [1]Quan Xie, et al. Preclinical Evaluation Study of 68Ga-Labeled PSMA-Targeted Dimer Probe. pubs.acs.org. 2025 Jun 10.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported