PSMA-DIM

CAT: 0804-HY-175248Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-175248Size:1 Each

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Description

PSMA-DIM is a dimeric PSMA ligand with a Kd of 37.09 nM for LNCaP cells. PSMA-DIM can be radiolabeled with [68Ga]Ga to form [68Ga]Ga-PSMA-DIM. [68Ga]Ga-PSMA-DIM can effectively distinguish between cells and animal models with different expression levels of PSMA. [68Ga]Ga-PSMA-DIM exhibits high LNCaP cells uptake and tumor uptake peak values. PSMA-DIM can be used for the study of prostate cancer (PCa) [1].

UNSPSC

12352211

Target

PSMA

Related Pathways

Immunology/Inflammation

Field of Research

Cancer

Smiles

IC1=CC=C(C=C1)CCCC(NCCCCC(C(NC(CCC(NCCOCCOCCOCCOCC(NC2CCN(C(N[C@H](C(NCCCC[C@@H](C(O)=O)NC(N[C@@H](CCC(O)=O)C(O)=O)=O)=O)CC3=CC=C4C=CC=CC4=C3)=O)CC2)=O)=O)C(NCCOCCOCCOCCOCC(NC5CCN(C(N[C@H](C(NCCCC[C@@H](C(O)=O)NC(N[C@@H](CCC(O)=O)C(O)=O)=O)=O)CC6=CC=C7C=CC=CC7=C6)=O)CC5)=O)=O)=O)NC(CN8CCN(CCN(CCN(CC8)CC(O)=O)CC(O)=O)CC(O)=O)=O)=O

Molecular Formula

C119H174IN21O39

Molecular Weight

2649.68

References & Citations

[1]Quan Xie, et al. Preclinical Evaluation Study of 68Ga-Labeled PSMA-Targeted Dimer Probe. pubs.acs.org. 2025 Jun 10.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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