DIM-C-pPhOCH3

• Description :

  DIM-C-pPhOCH3 is a Nur77 agonist. Nerve growth factor-induced Bα (NGFI-Bα, Nur77) is an orphan nuclear receptor.

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Nuclear Hormone Receptor 4A/NR4A

• Type :

  Reference compound

• Related Pathways :

  Vitamin D Related/Nuclear Receptor

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/DIM-C-pPhOCH3.html

• Purity :

  99.65

• Solubility :

  DMSO : ≥ 33.3 mg/mL

• Smiles :

  COC1=CC=C(C(C2=CNC3=C2C=CC=C3)C4=CNC5=C4C=CC=C5)C=C1

• Molecular Formula :

  C24H20N2O

• Molecular Weight :

  352.43

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Cho SD, et al. Nur77 agonists induce proapoptotic genes and responses in colon cancer cells through nuclear receptor-dependent and nuclear receptor-independent pathways. Cancer Res. 2007 Jan 15;67 (2) :674-83.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Nur77/NR4A1

• CAS Number :

  [33985-68-1]