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PSMA-11

CAT: 0804-HY-125399-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-125399-01Size:1 mg
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Description
PSMA-11 is a small molecule ligand that targets prostate-specific membrane antigen (PSMA) and has the ability to inhibit PSMA activity. PSMA-11 can be used to synthesize 68Ga-PSMA-11, a positron emission tomography (PET) tracer that can be used to image advanced prostate cancer[1][2][3].
CAS Number
1366302-52-4
Product Name Alternative
HBED-CC-PSMA
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
PSMA; Radionuclide-Drug Conjugates (RDCs)
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related; Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/psma-11.html
Purity
99.74
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC(CN(CCN(CC(O)=O)CC1=CC(CCC(O)=O)=CC=C1O)CC2=CC(CCC(NCCCCCC(NCCCC[C@@H](C(O)=O)NC(N[C@H](C(O)=O)CCC(O)=O)=O)=O)=O)=CC=C2O)=O
Molecular Formula
C44H62N6O17
Molecular Weight
946.99
Precautions
H302, H315, H319
References & Citations
[1]Demirci E, et al. Normal distribution pattern and physiological variants of 68Ga-PSMA-11 PET/CT imaging. Nucl Med Commun. 2016 Nov;37 (11) :1169-79.|[2]Eder M, et al. 68Ga-complex lipophilicity and the targeting property of a urea-based PSMA inhibitor for PET imaging[J]. Bioconjugate chemistry, 2012, 23 (4) : 688-697.|[3]Bois F, et al. [68Ga] Ga-PSMA-11 in prostate cancer: a comprehensive review[J]. American Journal of Nuclear Medicine and Molecular Imaging, 2020, 10 (6) : 349.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Isoform
Other

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