PSMA-BCH

• Description :

  PSMA-BCH (NOTA-PSMA) is a NOTA-conjugated precursor. NOTA is a bifunctional chelate which acts as the framework to construct PET imaging tools[1].

• Product Name Alternative :

  NOTA-PSMA

• UNSPSC :

  12352005

• Target :

  Radionuclide-Drug Conjugates (RDCs)

• Type :

  Reference compound

• Related Pathways :

  Antibody-drug Conjugate/ADC Related

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/psma-bch.html

• Purity :

  99.93

• Solubility :

  DMSO : 125 mg/mL (ultrasonic) |H2O : 5 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  O=C([C@@H]1CC[C@H](CC1)CNC(CN2CCN(CCN(CC2)CC(O)=O)CC(O)=O)=O)N[C@H](C(NCCCC[C@@H](C(O)=O)NC(N[C@H](C(O)=O)CCC(O)=O)=O)=O)CC3=CC4=C(C=CC=C4)C=C3

• Molecular Formula :

  C45H64N8O14

• Molecular Weight :

  941.03

• References & Citations :

  [1]Teli Liu, et al. Synthesis and preclinical evaluation of 68Ga-PSMA-BCH for prostate cancer imaging. Bioorg Med Chem Lett. 2019 Apr 1;29 (7) :933-937.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  RDC Bifunctional Chelator

• CAS Number :

  [1703768-73-3]