PQM-244

CAT: 0804-HY-174848Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-174848Size:1 Each
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Description
PQM-244 (Compound 5c) is an orally active and multi-target modulator of TRPV1 and CB1 and CB2 receptors. PQM-244 has significant peripheral antinociceptive effects on both neurogenic and inflammatory phases. PQM-244 also has potential antioxidant activity with an IC50 of 14.15 µM for radical scavenging DPPH. PQM-244 can be used for chronic pain and inflammatory disease research, such as diabetes, atherosclerosis and Alzheimer’s disease[1].
CAS Number
[316139-50-1]
UNSPSC
12352005
Target
Cannabinoid Receptor; TRP Channel
Related Pathways
GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Inflammation/Immunology; Neurological Disease
Smiles
CC1=CC[C@H](C(C)=C)C/C1=N\NC(C2=CC=C(OC)C=C2)=O
Molecular Formula
C18H22N2O2
Molecular Weight
298.38
References & Citations
[1]Dos Reis Rosa Franco G, et al. New cannabidiol structure-related terpene N-acyl-hydrazones with potent antinociceptive and anti-inflammatory activity. Future Med Chem. 2025 Jun 16:1-12.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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