NUV-244

• Target:

  Lipase

• Related Pathways:

  Metabolism

• Bioactivity:

  NUV-244 is a degrader of PNPLA3 I148M. It reduces the levels of PNPLA3 I148M on lipid droplets through BFAR-mediated ubiquitin-proteasome degradation.

• Smiles:

  CC1=CC=CC (CC2=NC (C) =C (C (NC3=CC (O) =CC=C3Cl) =O) S2) =C1

• Molecular Formula:

  C19H17ClN2O2S

• Molecular Weight:

  372.87

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C