PQM-164

• Bioactivity:

  PQM-164 (Compound 3e) exhibits antioxidative properties, demonstrated by its ability to scavenge DPPH free radicals with an IC50 of 0.93 ?M. This compound shows anti-inflammatory activity against neuronal damage induced by activated microglia due to 6-OHDA. Additionally, PQM-164 reduces the accumulation of ?-synuclein and enhances the nuclear translocation and transcriptional activity of Nrf2. PQM-164 is utilized in research related to Parkinsons disease.

• Smiles:

  C(=N/NC(/C=C/C1=CC(OC)=C(O)C=C1)=O)\C2=CC(OC)=C(O)C=C2

• Molecular Formula:

  C18H18N2O5

• Molecular Weight:

  342.35

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2226535-25-5