Products for Research Use Only
RegisterLogin

PQM-164

CAT: 0804-HY-159152Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-159152Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
PQM-164 (Compound 3e) has antioxidant activity (IC50: 0.93 μM for DPPH radical). PQM-164 shows anti-inflammatory activity against 6-OHDA -induced neuronal damage in activated microglial cells. PQM-164 decreases the accumulation of α-synuclein. PQM-164 promotes nuclear translocation of Nrf2 and its transcriptional activity. PQM-164 can be used for research of Parkinson’s disease[1].
CAS Number
2226535-25-5
UNSPSC
12352005
Target
α-synuclein
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pqm-164.html
Smiles
O=C(N/N=C/C1=CC=C(O)C(OC)=C1)/C=C/C2=CC=C(O)C(OC)=C2
Molecular Formula
C18H18N2O5
Molecular Weight
342.35
References & Citations
[1]de Freitas Silva M, et al. Synthesis and pharmacological evaluation of novel N-aryl-cinnamoyl-hydrazone hybrids designed as neuroprotective agents for the treatment of Parkinson's disease. Bioorg Chem. 2024 Sep;150:107587.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
α-synuclein Aggregation

Related Products

CatalogName
HY-174848PQM-244
HY-163562-01JYQ-164
HY-112182-01UM-164
HY-174826EGFR-IN-164
HY-138104-01SL-164
HY-15989-01SM-164
HY-162594Antitumor agent-164
HY-128634Anticancer agent 164
HY-15989A-01SM-164 (hydrochloride)
HY-157143Antibacterial agent 164

Alternative Products

CatalogName
T89390-01PQM-164
T211171-01PQM-244
BA3628-10UM-164
A8815-5SM-164
ABC-TC1285WEHI-164
PR15034VEGF 164
T211050-01EGFR-IN-164
ABC-TC1280WEHI 164

Popular Products