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Antibacterial agent 244

CAT: 0804-HY-162923Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-162923Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Antibacterial agent 244 is an orally active compound with broad-spectrum antibacterial activity, primarily targeting Gram-positive bacteria, with a MIC value of 1–4 μg/mL and low hemolytic toxicity (HC50 of 111.6 μg/mL) . Antibacterial agent 244 disrupts bacterial transmembrane potential, increases membrane permeability, leading to leakage of cellular contents such as DNA and proteins, ultimately causing bacterial death. Antibacterial agent 244 can be used in research related to Gram-positive bacterial infections[1].
CAS Number
9007-83-4
UNSPSC
12352211
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antibacterial-agent-244.html
Smiles
CC1(CC/C=C(C)/C)C=CC(C(OCC(NCCN(C)C)=O)=C(C(C)=O)C2=C3C=CC(C)(CC/C=C(C)/C)O2)=C3O1
Molecular Formula
C34H48N2O5
Molecular Weight
564.76
References & Citations
[1]Wang Y, et al. Design, synthesis, and evaluation of pyranochromene derivatives as membrane targeting antibacterials against Gram-positive bacteria. Bioorg Med Chem Lett. 2024 Sep 5;113:129949.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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