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DPP-4-IN-16

CAT: 0804-HY-174832Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-174832Size:1 Each
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Description
DPP-4-IN-16 (Compound 92) is a potent dipeptidyl peptidase-4 (DPP-4) inhibitor (IC50=0.8 nM) . DPP-4-IN-16 inhibits DPP-4-mediated degradation of incretins (e.g., GLP-1 and GIP) to promote insulin secretion and reduce blood glucose. DPP-4-IN-16 is promising for research of type 2 diabetes[1].
UNSPSC
12352005
Target
Dipeptidyl Peptidase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Smiles
[H]C1=C(N(C(N(C1=O)CC#CC)=O)N2CCC[C@@H](N)C2)CC3=C(Br)C=CC(C(O)=O)=C3
Molecular Formula
C21H23BrN4O4
Molecular Weight
475.34
References & Citations
[1]Kohal R, et al. Pyrimidine‐2, 4‐dione‐Based DPP‐4 Inhibitors: A Structure‐Guided Multifaced 3D‐QSAR and Molecular Dynamics Studies[J]. ChemistrySelect, 2025, 10 (22) : e00268.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
DPP-4

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