PRMT5 ligand 2

• Description:

  PRMT5 ligand 2 (Compound 38) is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs) . PRMT5 ligand 2 can be used for synthesis MS115 (HY-173561) [1].

• UNSPSC:

  12352005

• Target:

  Ligands for Target Protein for PROTAC

• Related Pathways:

  PROTAC

• Field of Research:

  Cancer

• Smiles:

  O=C(NC[C@@H](CN1CC2=C(CC1)C=CC=C2)O)C3=NC=NC(NC4CCNCC4)=C3

• Molecular Formula:

  C22H30N6O2

• Molecular Weight:

  410.51

• References & Citations:

  [1]Zhong Y, et al. Discovery of a Potent and Selective Protein Arginine Methyltransferase 5 (PRMT5) PROTAC Degrader. J Med Chem. 2025 Apr 24;68 (8) :8543-8563.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1616391-79-7]