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OSUAB-0284

CAT: 0804-HY-173478Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-173478Size:1 Each
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Description
OSUAB-0284 is a bacterial topoisomerase inhibitor. OSUAB-0284 has significant anti-staphylococcal activity, especially against methicillin-resistant Staphylococcus aureus (MRSA) . OSUAB-0284 exerts its antibacterial effect by inhibiting bacterial topoisomerase. OSUAB-0284 can be used to study infections caused by drug-resistant bacteria such as MRSA[1].
CAS Number
3053515-60-6
UNSPSC
12352005
Target
Antibiotic; Bacterial; Topoisomerase
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Field of Research
Infection
Smiles
O[C@@H](CC1=C(F)C=NC2=CC=C(OC)N=C12)[C@H](OC3)OC[C@@H]3NCC4=CN=C(OC5)C(NC5=O)=N4
Molecular Formula
C22H23FN6O6
Molecular Weight
486.45
References & Citations
[1]West JS, et al. Decagram-Scale Synthesis of the Novel Bacterial Topoisomerase Inhibitor OSUAB-0284. Org Process Res Dev. 2025 Mar 26;29 (4) :1136-1151.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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T207331-01OSUAB-0284
BA8321-25AZD-0284
A18766-50AZD-0284 50mg
A18766-100AZD-0284 100mg
A18766-25AZD-0284 25mg
A18766-5AZD-0284 5mg
A18766-10AZD-0284 10mg
A18766-1AZD-0284 1mg
A18766-10mM-DAZD-0284 10mM * 1mL in DMSO

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