OSUAB-0284

• Description:

  OSUAB-0284 is a bacterial topoisomerase inhibitor. OSUAB-0284 has significant anti-staphylococcal activity, especially against methicillin-resistant Staphylococcus aureus (MRSA) . OSUAB-0284 exerts its antibacterial effect by inhibiting bacterial topoisomerase. OSUAB-0284 can be used to study infections caused by drug-resistant bacteria such as MRSA[1].

• UNSPSC:

  12352005

• Target:

  Antibiotic; Bacterial; Topoisomerase

• Related Pathways:

  Anti-infection; Cell Cycle/DNA Damage

• Field of Research:

  Infection

• Smiles:

  O[C@@H](CC1=C(F)C=NC2=CC=C(OC)N=C12)[C@H](OC3)OC[C@@H]3NCC4=CN=C(OC5)C(NC5=O)=N4

• Molecular Formula:

  C22H23FN6O6

• Molecular Weight:

  486.45

• References & Citations:

  [1]West JS, et al. Decagram-Scale Synthesis of the Novel Bacterial Topoisomerase Inhibitor OSUAB-0284. Org Process Res Dev. 2025 Mar 26;29 (4) :1136-1151.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [3053515-60-6]