BI-0282

CAT: 0804-HY-150620Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-150620Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BI-0282 (Compound 1) is a potent MDM2-p53 interaction inhibitor[1].
CAS Number
[1883383-48-9]
UNSPSC
12352005
Target
MDM-2/p53
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bi-0282.html
Solubility
10 mM in DMSO
Smiles
FC1=C(C=CC=C1[C@@H]([C@@H]2N3C4=C5C=CC(C(O)=O)=CC5=N3)[C@]6(C(NC7=C6C=CC(Cl)=C7)=O)N([C@H]2CO4)CC8CC8)Cl
Molecular Formula
C30H23Cl2FN4O4
Molecular Weight
593.43
References & Citations
[1]Ramharter J, et al. Synthesis of MDM2-p53 Inhibitor BI-0282 via a Dipolar Cycloaddition and Late-Stage Davis–Beirut Reaction. Organic Process Research & Development, 2022.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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