BI-0282

• Description :

  BI-0282 (Compound 1) is a potent MDM2-p53 interaction inhibitor[1].

• UNSPSC :

  12352005

• Target :

  MDM-2/p53

• Type :

  Reference compound

• Related Pathways :

  Apoptosis

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/bi-0282.html

• Solubility :

  10 mM in DMSO

• Smiles :

  FC1=C(C=CC=C1[C@@H]([C@@H]2N3C4=C5C=CC(C(O)=O)=CC5=N3)[C@]6(C(NC7=C6C=CC(Cl)=C7)=O)N([C@H]2CO4)CC8CC8)Cl

• Molecular Formula :

  C30H23Cl2FN4O4

• Molecular Weight :

  593.43

• References & Citations :

  [1]Ramharter J, et al. Synthesis of MDM2-p53 Inhibitor BI-0282 via a Dipolar Cycloaddition and Late-Stage Davis–Beirut Reaction. Organic Process Research & Development, 2022.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1883383-48-9]