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BMS-185354

CAT: 0804-HY-173159Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-173159Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BMS-185354 is a selective RARγ activator with an EC50 value of 28 nM. BMS-185354 is promising for research of cancers[1].
CAS Number
110952-22-2
UNSPSC
12352005
Target
RAR/RXR
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Smiles
O=C(C1=CC2=CC=C(/C(C3=CC=C4C(C(C)(CCC4(C)C)C)=C3)=N/O)C=C2C=C1)O
Molecular Formula
C26H27NO3
Molecular Weight
401.50
References & Citations
[1]Ostrowski J, et al. Serine 232 and methionine 272 define the ligand binding pocket in retinoic acid receptor subtypes. J Biol Chem. 1998 Feb 6;273 (6) :3490-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
RXRγ

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