LSD1-IN-42

• Target:

  Histone Demethylase|||PD-1/PD-L1

• Related Pathways:

  Chromatin/Epigenetic|||Apoptosis|||Immunology/Inflammation|||Cell Cycle/Checkpoint

• Bioactivity:

  LSD1-IN-42 (Compound 7ae) is an orally active LSD1 inhibitor that significantly suppresses LSD1 activity (IC50 = 0.08 ?M) . It reduces PD-L1 expression and enhances the tumor-killing effect of T cells. LSD1-IN-42 demonstrates notable anti-gastric cancer activity by inhibiting tumor cell invasion and migration.

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C