CFTR corrector 18

• Description:

  CFTR corrector 18 (Compound I-99) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector. CFTR corrector 18 facilitates the processing and trafficking of CFTR, increasing the number of CFTR on the cell surface. CFTR corrector 18 is promising for research of cystic fibrosis (CF) [1].

• UNSPSC:

  12352005

• Target:

  CFTR

• Related Pathways:

  Membrane Transporter/Ion Channel

• Field of Research:

  Endocrinology

• Smiles:

  CC(C)(C)C1=CC2=NC(CN(C(C3=CC(S(=O)(NC4=NC(C5=C(C=CC=C5C)C)=CC(OC6)=N4)=O)=CC=C3)=O)[C@@H]6CC78CC(C8)C7)=CN=C2O1

• Molecular Formula:

  C38H40N6O5S

• Molecular Weight:

  692.83

• References & Citations:

  [1]Alexander Russell Abela, et al. Modulators of cystic fibrosis transmembrane conductance regulator. WO2023196429A1. 2023-10-12.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2993441-49-7