Products for Research Use Only
RegisterLogin

CFTR corrector 4

CAT: 0804-HY-135279-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-135279-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CFTR corrector 4 (Compound 13), an active (R, R) -form enantiomer, is a highly potent and orally active cystic fibrosis transmembrane conductance regulator (CFTR) corrector. CFTR corrector 4 can increase CFTR levels at the cell surface and have the potential for treatment of cystic fibrosis[1].
CAS Number
1918142-34-3
UNSPSC
12352005
Target
CFTR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cftr-corrector-4.html
Purity
99.72
Solubility
DMSO : 110 mg/mL (ultrasonic)
Smiles
O=C(C1(C2=CC=C(OC(F)(F)O3)C3=C2)CC1)N[C@@H]4C[C@H](C5=CC=C(OC)C(OC)=C5)OC6=CC(OC)=CC=C46
Molecular Formula
C29H27F2NO7
Molecular Weight
539.52
References & Citations
[1]Wang X, et al. Discovery of 4-[ (2R,4R) -4- ({[1- (2,2-Difluoro-1,3-benzodioxol-5-yl) cyclopropyl]carbonyl}amino) -7- (difluoromethoxy) -3,4-dihydro-2H-chromen-2-yl]benzoic Acid (ABBV/GLPG-2222), a Potent Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Corrector for the Treatment of Cystic Fibrosis.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-153133-01CFTR corrector 11
HY-161895CFTR corrector 14
HY-W984122-01CFTR corrector 17
HY-164000-01CFTR corrector 15
HY-136939-01CFTR corrector 6
HY-147315-01CFTR corrector 9
HY-161894CFTR corrector 13
HY-147249-01CFTR corrector 8
HY-172555CFTR corrector 18
HY-125381-01CFTR corrector 2

Alternative Products

CatalogName
T89966-01CFTR corrector 15
T89320-01CFTR corrector 14
T63806-01CFTR corrector 8
MBS3842992-01CFTR corrector 2
MBS5821240CFTR corrector 12
GTR19239252-01CFTR corrector 16
GTR19258221-01CFTR corrector 18
T89629-01CFTR corrector 13
T10776-01CFTR corrector 4
GTR19187816-01CFTR corrector 9

Popular Products