PSB-0788

• Description :

  PSB-0788 is a new selective high-affinity A2B antagonist with IC50 value of 3.64 nM and Ki value of 0.393 nM, respeactively. PSB-0788 can be used for the research for chronic inflammatory lung diseases[1].

• UNSPSC :

  12352005

• Target :

  Adenosine Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Cancer; Infection

• Assay Protocol :

  https://www.medchemexpress.com/psb-0788.html

• Purity :

  99.68

• Solubility :

  DMSO : 125 mg/mL (ultrasonic)

• Smiles :

  O=C1NC2=C(C(N1CCC)=O)NC(C3=CC=C(S(=O)(N4CCN(CC4)CC5=CC=C(C=C5)Cl)=O)C=C3)=N2

• Molecular Formula :

  C25H27ClN6O4S

• Molecular Weight :

  543.04

• References & Citations :

  [1]Thomas Borrmann, et al. 1-alkyl-8- (piperazine-1-sulfonyl) phenylxanthines: development and characterization of adenosine A2B receptor antagonists and a new radioligand with subnanomolar affinity and subtype specificity. J Med Chem. 2009 Jul 9;52 (13) :3994-4006.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1027513-54-7]