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PI3K-IN-56

CAT: 0804-HY-171558Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-171558Size:1 Each
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Description
PI3K-IN-56 (Compound 1) is an orally active, potent and selective irreversible inhibitor of phosphoinositide 3-kinase (PI3K) . PI3K-IN-56 irreversibly blocks the phosphatidylinositol-3,4,5-triphosphate (PIP3) production and downstream AKT signaling pathway. PI3K-IN-56 is promising for research of PI3Kα-driven cancers, such as breast and ovarian cancers[1].
CAS Number
2633645-58-4
UNSPSC
12352005
Target
Akt; PI3K
Related Pathways
PI3K/Akt/mTOR
Field of Research
Cancer
Smiles
O=C(NC1=CC(C(F)(F)F)=C(C2=NN3C=C(CN4CCN(CC4)C(CNC(C=C)=O)=O)C=C3C(N5CCOCC5)=N2)C=N1)OC
Molecular Formula
C28H32F3N9O5
Molecular Weight
631.61
References & Citations
[1]Neil Sonin DHAWAN, et al. Crystalline forms and salts of a pi3k inhibitor and methods of making and methods of use thereof. WO2023179771A1. 2023-09-28.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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