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PI3Kδ-IN-5

CAT: 0804-HY-122593-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-122593-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PI3Kδ-IN-5 (compound 7n) is a highly potent and selective inhibitor of PI3Kδ with an IC50 of 0.9 nM[1].
CAS Number
2088525-31-7
UNSPSC
12352005
Target
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pi3kδ-in-5.html
Purity
99.62
Solubility
DMSO : 41.67 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(N)C1=CC=C(C2=NC(C3=NN(C)C(C4(C5=CC=CC=C5)CC4)=N3)=CN=C2N)C=C1F
Molecular Formula
C23H20FN7O
Molecular Weight
429.45
References & Citations
[1]Terstiege I, et al. Discovery of triazole aminopyrazines as a highly potent and selective series of PI3Kδ inhibitors. Bioorg Med Chem Lett. 2017;27 (3) :679-687.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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