PI3Kδ-IN-5

• UNSPSC Description:

  PI3Kδ-IN-5 (compound 7n) is a highly potent and selective inhibitor of PI3Kδ with an IC50 of 0.9 nM[1].

• Target Antigen:

  PI3K

• Type:

  Reference compound

• Related Pathways:

  PI3K/Akt/mTOR

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/pi3kδ-in-5.html

• Purity:

  99.62

• Solubility:

  DMSO : 41.67 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  O=C(N)C1=CC=C(C2=NC(C3=NN(C)C(C4(C5=CC=CC=C5)CC4)=N3)=CN=C2N)C=C1F

• Molecular Weight:

  429.45

• References & Citations:

  [1]Terstiege I, et al. Discovery of triazole aminopyrazines as a highly potent and selective series of PI3Kδ inhibitors. Bioorg Med Chem Lett. 2017;27(3):679-687.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  2088525-31-7