PI3K-IN-48
CAT:
804-HY-156080
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PI3K-IN-48
- UNSPSC Description: PI3K-IN-48 is a PI3K inhibitor with IC50 value of 1.55 ± 0.18 μM for A549 cells. PI3K-IN-48 can induce G0/G1 phase arrest, cell apoptosis, and down-regulate expression of p-PI3K and p-Akt. PI3K-IN-48 can be used for human lung cancers diseases research[1].
- Target Antigen: Akt; PI3K
- Type: Reference compound
- Related Pathways: PI3K/Akt/mTOR
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/pi3k-in-48.html
- Solubility: 10 mM in DMSO
- Smiles: COC1=CC(OC)=C(C=C1C2=NC3=CC(OC)=C(C=C3N2)C#CC4=C(C=CC=C4)F)OC
- Molecular Weight: 432.44
- References & Citations: [1]Wu W, et al. Design, synthesis and antitumor effects of novel benzimidazole derivatives as PI3K inhibitors. Bioorg Med Chem Lett. 2023 Sep 7;95:129469.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported