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PI3K-IN-38

CAT: 0804-HY-150034-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-150034-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PI3K-IN-38 (compound 123) is an orally active PI3K inhibitor with IC50 of 0.541 µM (PI3K-α) . PI3K-IN-38 shows activities of anticancer and anti-inflammatory, which inhibis tumor growth in vivo[1].
CAS Number
1382979-64-7
UNSPSC
12352005
Target
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pi3k-in-38.html
Solubility
10 mM in DMSO
Smiles
CC1(C)OCCN2C1=NC3=C(N4CCOCC4)N=C(C5=CC=C(N)C=C5)N=C23
Molecular Formula
C20H24N6O2
Molecular Weight
380.44
References & Citations
[1]Dotson J, et al. Tricyclic pi3k inhibitor compounds and methods of use. WO2012082997A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PI3Kα

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