PI3K-IN-38

• UNSPSC Description:

  PI3K-IN-38 (compound 123) is an orally active PI3K inhibitor with IC50 of 0.541 µM (PI3K-α). PI3K-IN-38 shows activities of anticancer and anti-inflammatory, which inhibis tumor growth in vivo[1].

• Target Antigen:

  PI3K

• Type:

  Reference compound

• Related Pathways:

  PI3K/Akt/mTOR

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/pi3k-in-38.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1(C)OCCN2C1=NC3=C(N4CCOCC4)N=C(C5=CC=C(N)C=C5)N=C23

• Molecular Weight:

  380.44

• References & Citations:

  [1]Dotson J, et al. Tricyclic pi3k inhibitor compounds and methods of use. WO2012082997A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1382979-64-7