Lp (a) -IN-5

CAT: 0804-HY-171464Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-171464Size:1 Each
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Description
Lp (a) -IN-5 (Compound A) is an orally active lipoprotein (a) (Lp (a) ) inhibitor. Lp (a) -IN-5 inhibits the assembly of Apo (a) and ApoB proteins with an IC50 value of 0.41 nM. Lp (a) -IN-5 is promising for research of diseases related to elevated plasma Lp (a) levels, such as cardiovascular diseases[1].
CAS Number
[2924841-79-0]
UNSPSC
12352211
Target
Apolipoprotein
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Smiles
O=C(O)[C@H]([C@H]1CCNC1)CC2=CC=CC(CN(CC3=CC(C[C@H](C(O)=O)[C@H]4CCNC4)=CC=C3)CCOC5=CC(C[C@H](C(O)=O)[C@H]6CCNC6)=CC=C5)=C2
Molecular Formula
C43H56N4O7
Molecular Weight
740.93
References & Citations
[1]Yao JQ, et al. Crystal form of lipoprotein compound and preparation method therefor. WO2024230805A1. 2024-11-14.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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