MAT2A-IN-20

• Target:

  Methionine Adenosyltransferase (MAT)

• Related Pathways:

  Chromatin/Epigenetic

• Bioactivity:

  MAT2A-IN-20 (Compound A49) is an inhibitor of methionine adenosyltransferase 2A (MAT2A) with an IC50 of ?50 nM. It also inhibits human UGT1A1 with an IC50 of 28.45 ?M. Additionally, MAT2A-IN-20 exhibits antitumor activity in mouse models.

• Smiles:

  O=C1C (=NC=2C=NC (=NC2N1C3=CC=C (OC (F) F) C=C3) OCC) C=4C=CC=5N=C (N (C5C4) C) C (O) (C) C

• Molecular Formula:

  C26H24F2N6O4

• Molecular Weight:

  522.503

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3018834-98-2