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MAT2A-IN-20

CAT: 0931-T204278-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T204278-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3018834-98-2
Target
Methionine Adenosyltransferase (MAT)
Related Pathways
Chromatin/Epigenetic
Bioactivity
MAT2A-IN-20 (Compound A49) is an inhibitor of methionine adenosyltransferase 2A (MAT2A) with an IC50 of ≤50 nM. It also inhibits human UGT1A1 with an IC50 of 28.45 μM. Additionally, MAT2A-IN-20 exhibits antitumor activity in mouse models.
Smiles
O=C1C(=NC=2C=NC(=NC2N1C3=CC=C(OC(F)F)C=C3)OCC)C=4C=CC=5N=C(N(C5C4)C)C(O)(C)C
Molecular Formula
C26H24F2N6O4
Molecular Weight
522.503
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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