BAY-277

• Description:

  BAY-277, a chemical probe, is a METAP2 degrader, with IC50 values of 5.8 nM and 5.9 nM for hMETAP2 and mMETAP2, respectively[1].

• UNSPSC:

  12352211

• Target:

  MetAP

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Smiles:

  O=C(N1CCC(C2=CC=C3C(CN(C4C(NC(CC4)=O)=O)C3=O)=C2)CC1)CCCCCN(CC5)CCC5C6=CC=C(C=C6)OC7=NN8C(C9=C7CCCC9)=NN=C8

• Molecular Formula:

  C44H52N8O5

• Molecular Weight:

  772.93

• References & Citations:

  [1]Overview for BAY-277 a degrader of METAP2.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported