BAY-277

CAT: 0804-HY-168967Size: 1 EachDry Ice: NoHazardous: No

CAT#:0804-HY-168967Size:1 Each

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Description

BAY-277, a chemical probe, is a METAP2 degrader, with IC50 values of 5.8 nM and 5.9 nM for hMETAP2 and mMETAP2, respectively[1].

UNSPSC

12352211

Target

MetAP

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O=C(N1CCC(C2=CC=C3C(CN(C4C(NC(CC4)=O)=O)C3=O)=C2)CC1)CCCCCN(CC5)CCC5C6=CC=C(C=C6)OC7=NN8C(C9=C7CCCC9)=NN=C8

Molecular Formula

C44H52N8O5

Molecular Weight

772.93

References & Citations

[1]Overview for BAY-277 a degrader of METAP2.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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