CB10-277

• CAS Number :

  7203-91-0

• Target :

  Others|||DNA Alkylator/Crosslinker|||Nucleoside Antimetabolite/Analog

• Related Pathways :

  Others|||DNA Damage/DNA Repair|||Cell Cycle/Checkpoint

• Bioactivity :

  CB10-277 is a synthetic derivative of dimethylphenyl-triazene related to dacarbazine, with antineoplastic properties. Related to the agent dacarbazine, CB10-277 is converted in vivo to a monomethyl triazene form that alkylates DNA, resulting in inhibition of DNA replication and repair; in addition, this agent may act as a purine analogue, resulting in inhibition of DNA synthesis, and may interact with protein sulfhydryl groups.

• Smiles :

  CN(C)\N=N\C1=CC=C(C=C1)C(O)=O

• Molecular Formula :

  C9H11N3O2

• Molecular Weight :

  193.2

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C