CB10-277

CAT: 0931-T71768-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T71768-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
7203-91-0
Target
Others|||DNA Alkylator/Crosslinker|||Nucleoside Antimetabolite/Analog
Related Pathways
Others|||DNA Damage/DNA Repair|||Cell Cycle/Checkpoint
Bioactivity
CB10-277 is a synthetic derivative of dimethylphenyl-triazene related to dacarbazine, with antineoplastic properties. Related to the agent dacarbazine, CB10-277 is converted in vivo to a monomethyl triazene form that alkylates DNA, resulting in inhibition of DNA replication and repair; in addition, this agent may act as a purine analogue, resulting in inhibition of DNA synthesis, and may interact with protein sulfhydryl groups.
Smiles
CN(C)\N=N\C1=CC=C(C=C1)C(O)=O
Molecular Formula
C9H11N3O2
Molecular Weight
193.2
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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