Bml 277

• Background:

  Bml 277 is a highly selective inhibitor of Chk2, making it a useful tool for dissecting the role of Chk2 in cellular signaling.

• Description:

  CHK2 kinase inhibitor

• Product Name Alternative:

  Chk2 Inhibitor II, Chk2 Inhibitor II hydrate, 2- (4- (4-Chlorophenoxy) phenyl) -1H-benzimidazole-5-carboxamide hydrate

• UNSPSC:

  41116105

• Type:

  Inhibitor

• Source:

  Synthetic

• Field of Research:

  Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

• Purity:

  ≥98% (TLC)

• Weight:

  0.05

• Format:

  Off-white solid

• Solubility:

  Soluble in DMSO (20 mg/ml) or ethanol (20 mg/ml)

• Molecular Formula:

  C20H14ClN3O2

• Molecular Weight:

  363.8

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Pereg Y., et al. (2006) Mol. Cell Biol. 26(18): 6819–6831.

• CAS Number:

  516480-79-8