BAY-386

• Description :

  BAY-386, a chemical probe, is a PAR-1 antagonist that inhibits the expression of pro-inflammatory factors MCP-1 and CXCL1 in HUVEC[1].

• UNSPSC :

  12352005

• Target :

  Protease Activated Receptor (PAR)

• Related Pathways :

  GPCR/G Protein

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Smiles :

  O=C(N1C[C@@H](C2=NC(C3CC3)=NO2)C[C@@H](C4=CC=C(OC(F)(F)F)C=C4)C1)N5CCS(CC5)(=O)=O

• Molecular Formula :

  C22H25F3N4O5S

• Molecular Weight :

  514.52

• References & Citations :

  [1]Santos S R F. Impact of PAR-1 upregulation upon EXT-1kd on balancing resistance and platelet activation[D]. Universidade de Lisboa (Portugal), 2022.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1256941-06-6]