BML-277

CAT: 0804-HY-13946-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-13946-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BML-277 is a selective checkpoint kinase 2 (Chk2) inhibitor with an IC50 of 15 nM.
CAS Number
[516480-79-8]
Product Name Alternative
Chk2 Inhibitor II
UNSPSC
12352005
Hazard Statement
H302, H315, H320, H335
Target
Apoptosis; Checkpoint Kinase (Chk)
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/BML-277.html
Purity
99.74
Solubility
DMSO : 22.22 mg/mL (ultrasonic)
Smiles
ClC(C=C1)=CC=C1OC(C=C2)=CC=C2C3=NC4=CC(C(N)=O)=CC=C4N3
Molecular Formula
C20H14ClN3O2
Molecular Weight
363.80
Precautions
H302, H315, H320, H335
References & Citations
[1]Arienti KL, et al. Checkpoint kinase inhibitors: SAR and radioprotective properties of a series of 2-arylbenzimidazoles. J Med Chem. 2005 Mar 24;48 (6) :1873-85.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Chk2

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