ABCB1-IN-4

• Description:

  ABCB1-IN-4 (Compound C6z) is an orally active and potent dual α-amylase and α-glucosidase inhibitor with IC50 values of 1.63 μM and 0.14 μM, respectively. ABCB1-IN-4 is promising for research of diabetes[1].

• UNSPSC:

  12352005

• Target:

  Amylases; Glycosidase

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Metabolic Disease

• Smiles:

  CNC1=NN=C(S1)CN2C3=C(C=CC=C3)C4=C2C=CC=C4

• Molecular Formula:

  C16H14N4S

• Molecular Weight:

  294.37

• References & Citations:

  [1]Çapan İ, et al. Novel carbazole-thiadiazole derivatives as α-amylase and α-glucosidase inhibitors: Design, biological evaluation, and computational insights. Bioorg Chem. 2025 Feb 12;157:108243.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Glucosidase

• CAS Number:

  [1500779-21-4]