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ABCB1-IN-1

CAT: 0804-HY-149366Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-149366Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ABCB1-IN-1 (compound 3) is a potent ABCB1 inhibitor. ABCB1-IN-1 induces cell apoptosis. ABCB1-IN-1 bearing 1-benzylimidazole has IC50 values of 1.26 μM and 2.21 μM for Colo205 and Colo320 cells, respectively[1].
CAS Number
2986412-70-6
UNSPSC
12352005
Target
P-glycoprotein
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/abcb1-in-1.html
Solubility
10 mM in DMSO
Smiles
O=S([O-])(C(F)(F)F)=O.[O]#C[Fe+2]1234([CH-]5[CH]1=[CH]2[CH]3=[CH]45)([N](C=C6)=CN6CC7=CC=CC=C7)[P](C8=CC=CC=C8)(C9=CC=CC=C9)C%10=CC=CC=C%10
Molecular Formula
C35H30F3FeN2O4PS
Molecular Weight
718.50
References & Citations
[1]Adhan Pilon, et al. First iron (II) organometallic compound acting as ABCB1 inhibitor. Eur J Med Chem. 2023 Aug 5;256:115466.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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