PKM2 modulator 1

• Description :

  PKM2 modulator 1 (compound C998) is a potent PKM2 inhibitor. PKM2 modulator 1 shows antiproliferative activity. PKM2 modulator 1 induces apoptosis. PKM2 modulator 1 has the potential for the research of glioblastoma[1].

• UNSPSC :

  12352211

• Target :

  Apoptosis; Pyruvate Kinase

• Related Pathways :

  Apoptosis; Metabolic Enzyme/Protease

• Field of Research :

  Cancer

• Smiles :

  O=C(NC[C@@H](C1=CNC2=C1C=CC=C2)C3=CC=CC=C3)NC[C@H]4OC5=CC=CC=C5OC4

• Molecular Formula :

  C26H25N3O3

• Molecular Weight :

  427.50

• References & Citations :

  [1]Maia Cabrera, et al. CADD-based discovery of novel oligomeric modulators of PKM2 with antitumor activity in aggressive human glioblastoma models. ScienceDirect. 2025.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported