PKM2 modulator 1

• Description:

  PKM2 modulator 1 (compound C998) is a potent PKM2 inhibitor. PKM2 modulator 1 shows antiproliferative activity. PKM2 modulator 1 induces apoptosis. PKM2 modulator 1 has the potential for the research of glioblastoma[1].

• UNSPSC:

  12352211

• Target:

  Apoptosis; Pyruvate Kinase

• Related Pathways:

  Apoptosis; Metabolic Enzyme/Protease

• Field of Research:

  Cancer

• Smiles:

  O=C(NC[C@@H](C1=CNC2=C1C=CC=C2)C3=CC=CC=C3)NC[C@H]4OC5=CC=CC=C5OC4

• Molecular Formula:

  C26H25N3O3

• Molecular Weight:

  427.50

• References & Citations:

  [1]Maia Cabrera, et al. CADD-based discovery of novel oligomeric modulators of PKM2 with antitumor activity in aggressive human glioblastoma models. ScienceDirect. 2025.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported