DPC-082

• Description :

  DPC-082 is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) of HIV-1. DPC-082 inhibits wild-type RF virus with an IC90 of 2.0 nM. DPC-082 inhibits various single and many multiple amino acid substituted HIV-1 mutant viruses[1].

• UNSPSC :

  12352005

• Target :

  HIV; Reverse Transcriptase

• Related Pathways :

  Anti-infection

• Field of Research :

  Infection

• Smiles :

  FC(F)(F)[C@@]1(C2=C(F)C(F)=CC=C2NC(N1)=O)/C=C/C3CC3

• Molecular Formula :

  C14H11F5N2O

• Molecular Weight :

  318.24

• References & Citations :

  [1]Corbett JW, et al. Inhibition of clinically relevant mutant variants of HIV-1 by quinazolinone non-nucleoside reverse transcriptase inhibitors. J Med Chem. 2000 May 18;43 (10) :2019-30.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  HIV-1

• CAS Number :

  [214287-98-6]