Products for Research Use Only
RegisterLogin

DPC-082

CAT: 0804-HY-167135Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-167135Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
DPC-082 is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) of HIV-1. DPC-082 inhibits wild-type RF virus with an IC90 of 2.0 nM. DPC-082 inhibits various single and many multiple amino acid substituted HIV-1 mutant viruses[1].
CAS Number
214287-98-6
UNSPSC
12352005
Target
HIV; Reverse Transcriptase
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
FC(F)(F)[C@@]1(C2=C(F)C(F)=CC=C2NC(N1)=O)/C=C/C3CC3
Molecular Formula
C14H11F5N2O
Molecular Weight
318.24
References & Citations
[1]Corbett JW, et al. Inhibition of clinically relevant mutant variants of HIV-1 by quinazolinone non-nucleoside reverse transcriptase inhibitors. J Med Chem. 2000 May 18;43 (10) :2019-30.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HIV-1

Chemical Information

Dpc-082
CAS Number214287-98-6
PubChem CID6451134
IUPAC Name(4S)-4-[(E)-2-cyclopropylethenyl]-5,6-difluoro-4-(trifluoromethyl)-1,3-dihydroquinazolin-2-one
Molecular FormulaC14H11F5N2O
Molecular Weight318.24
XLogP3.3
Topological Polar Surface Area41.1
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count2
Heavy Atom Count22
Formal Charge0
Complexity490
SMILES
C1CC1/C=C/[C@]2(C3=C(C=CC(=C3F)F)NC(=O)N2)C(F)(F)F
InChI
InChI=1S/C14H11F5N2O/c15-8-3-4-9-10(11(8)16)13(14(17,18)19,21-12(22)20-9)6-5-7-1-2-7/h3-7H,1-2H2,(H2,20,21,22)/b6-5+/t13-/m0/s1
InChIKey
JUCDJPCFPITYRP-GFUIURDCSA-N
Chemical Structure
2D Structure
2D structure of Dpc-082
CAS: 214287-98-6
CID: 6451134
Formula: C14H11F5N2O
MW: 318.24
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight318.24
XLogP33.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count2
Exact Mass318.07915379
Monoisotopic Mass318.07915379
Topological Polar Surface Area41.1 Ų
Heavy Atom Count22
Formal Charge0
Complexity490
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-114243-01DpC
HY-P1418DPC-AJ1951
HY-171835DPC 684
HY-19400-01DPC-681
HY-117477DPC 963
HY-19501DPC-168
HY-107001-01DPC 961
HY-123070-01ONO-RS-082
HY-P1418A-01DPC-AJ1951 (TFA)
HY-175875HRZ-01-082-5

Alternative Products

CatalogName
T27201-01DPC-082
GTR19214534-01DpC
BA1951-10DPC-681
TMB51933-01DPC AJ1951
T68245-01PA-082
T211711-01DPC 684
447698-01DPC 961
TRC-D585490-25MGDPC 083
GTR19197742-01DPC-423
GTR19197740-01DPC-963

Popular Products