Products for Research Use Only
RegisterLogin

DPC 684

CAT: 0804-HY-171835Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-171835Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
DPC 684 is a potent and selective HIV-1 protease inhibitor (IC90 = 5.7-40 nM, Ki = 0.021 nM) . DPC 684 competitively inhibits HIV-1 protease and blocks viral polyprotein cleavage. DPC 684 has low protein binding and broad-spectrum inhibition against a variety of wild-type and mutant HIV-1 proteases. DPC 684 has low protein binding and broad-spectrum inhibition (IC90 = 1.9-6.3 nM) . DPC 684 has research significance for HIV[1].
CAS Number
284661-73-0
UNSPSC
12352005
Target
HIV; HIV Protease
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Smiles
O=S(N(CC(C)C)C[C@@H](O)[C@@H](NC([C@H](C(C)(C)C)NC(CNCC1=CC(F)=CC=C1)=O)=O)CC2=CC=CC=C2)(C3=CC=C(C=C3)N)=O
Molecular Formula
C35H48FN5O5S
Molecular Weight
669.85
References & Citations
[1]R F Kaltenbach 3rd, et al. DPC 681 and DPC 684: potent, selective inhibitors of human immunodeficiency virus protease active against clinically relevant mutant variants. Antimicrob Agents Chemother. 2001 Nov;45 (11) :3021-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HIV-1

Related Products

CatalogName
HY-114243-01DpC
HY-167135DPC-082
HY-P1418DPC-AJ1951
HY-19400-01DPC-681
HY-173573TK-684
HY-117477DPC 963
HY-19501DPC-168
HY-107001-01DPC 961
HY-149665-01BMS-684
HY-P1418A-01DPC-AJ1951 (TFA)

Alternative Products

CatalogName
CN-A038-500GMAgar, Micropropagation - Type I (Gracilaria)
M2302-20HPhaseShield™ Gel Tubes, Heavy (200x 2ml)
M2302-20LPhaseShield™ Gel Tubes, Light (200x 2ml)
BCS81BioCoupler® Glass Set (8 oz) x1
E-EL-H1579ELISA kit for Human PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9)
E-EL-M0380ELISA kit for Mouse CDKN1B (Cyclin Dependent Kinase Inhibitor 1B)
EA-IP-017MProtein L Magnetic beads
E-KAB-0415Human CA9 Antibody Pair Set
E-EL-M2699ELISA kit for Mouse ACTN1 (Actinin Alpha 1)
E-EL-H1851ELISA kit for Human DSG1 (Desmogleins 1)

Popular Products