DPC 963

• Description :

  DPC-963 is an oral active non-nucleoside reverse transcriptase inhibitor with the IC50 of 18 nM. DPC-963 can be used for study of HIV[1][2].

• UNSPSC :

  12352005

• Target :

  HIV; Reverse Transcriptase

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/dpc-963.html

• Smiles :

  FC(F)(F)[C@@]1(C2=C(F)C(F)=CC=C2NC(N1)=O)C#CC3CC3

• Molecular Formula :

  C14H9F5N2O

• Molecular Weight :

  316.23

• References & Citations :

  [1]Corbett JW, et al. Expanded-spectrum nonnucleoside reverse transcriptase inhibitors inhibit clinically relevant mutant variants of human immunodeficiency virus type 1. Antimicrob Agents Chemother. 1999;43 (12) :2893-2897. |[2]Corbett JW, et al. Inhibition of clinically relevant mutant variants of HIV-1 by quinazolinone non-nucleoside reverse transcriptase inhibitors. J Med Chem. 2000;43 (10) :2019-2030.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [214287-90-8]