DPC 963

• Description:

  DPC-963 is an oral active non-nucleoside reverse transcriptase inhibitor with the IC50 of 18 nM. DPC-963 can be used for study of HIV[1][2].

• UNSPSC:

  12352005

• Target:

  HIV; Reverse Transcriptase

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/dpc-963.html

• Smiles:

  FC (F) (F) [C@@]1 (C2=C (F) C (F) =CC=C2NC (N1) =O) C#CC3CC3

• Molecular Formula:

  C14H9F5N2O

• Molecular Weight:

  316.23

• References & Citations:

  [1]Corbett JW, et al. Expanded-spectrum nonnucleoside reverse transcriptase inhibitors inhibit clinically relevant mutant variants of human immunodeficiency virus type 1. Antimicrob Agents Chemother. 1999;43 (12) :2893-2897. |[2]Corbett JW, et al. Inhibition of clinically relevant mutant variants of HIV-1 by quinazolinone non-nucleoside reverse transcriptase inhibitors. J Med Chem. 2000;43 (10) :2019-2030.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  214287-90-8