DpC

• Description :

  DpC is an anti-tumor agent. DpC inhibits cancer cell proliferation (IC50: 0.007-0.096 μM) . DpC synergizes with multiple anti-cancer therapeutics[1].

• Product Name Alternative :

  Adonitol-3-13C; Adonite-3-13C, Adonitol-5-13C; Adonite-5-13C

• UNSPSC :

  12352005

• Hazard Statement :

  H301

• Target :

  Others

• Type :

  Reference compound

• Related Pathways :

  Others

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/dpc.html

• Purity :

  98.73

• Solubility :

  DMSO : 62.5 mg/mL (ultrasonic)

• Smiles :

  S=C(N/N=C(C1=NC=CC=C1)\C2=NC=CC=C2)N(C3CCCCC3)C

• Molecular Formula :

  C19H23N5S

• Molecular Weight :

  353.48

• Precautions :

  H301

• References & Citations :

  [1]Dharmasivam M, et al. The thiosemicarbazone, DpC, broadly synergizes with multiple anti-cancer therapeutics and demonstrates temperature- and energy-dependent uptake by tumor cells. Biochim Biophys Acta Gen Subj. 2022 Aug;1866 (8) :130152.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 4

• CAS Number :

  [1382469-39-7]