(6E) -SR 11302

• Description:

  (6E) -SR 11302 is a E-isomer of SR 11302. SR 11302 is an activator protein-1 (AP-1) transcription factor inhibitor. SR 11302 is a retinoid that specifically inhibits AP-1 activity without activating the transcription of retinoic acid response element (RARE) [1].

• UNSPSC:

  12352211

• Target:

  AP-1

• Related Pathways:

  Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Inflammation/Immunology

• Purity:

  99.68

• Smiles:

  CC1 (C) C (/C=C/C (C2=CC=C (C=C2) C) =C\C=C\C (C) =C\C (O) =O) =C (C) CCC1

• Molecular Formula:

  C26H32O2

• Molecular Weight:

  376.53

• References & Citations:

  [1]C Huang, et al. Blocking activator protein-1 activity, but not activating retinoic acid response element, is required for the antitumor promotion effect of retinoic acid. Proc Natl Acad Sci U S A. 1997 May 27;94 (11) :5826-30.

• Shipping Conditions:

  Dry Ice

• Storage Conditions:

  -80°C, protect from light

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  1386982-70-2