Products for Research Use Only
RegisterLogin

SBI-0087702

CAT: 0804-HY-134963-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-134963-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SBI-0087702 promots the cytoplasmic localization of ATF2 in melanoma cells. SBI-0087702-induced translocation of ATF2 to the mitochondria results in increased apoptosis due to loss of mitochondrial membrane integrity. SBI-0087702 also inhibits growth and motility of melanoma cells. SBI-0087702 was shown to inhibit ATF2 phosphorylation on Thr52 by PKCε[1].
CAS Number
864431-36-7
UNSPSC
12352005
Hazard Statement
H318, H410
Target
PKC
Related Pathways
Epigenetics; TGF-beta/Smad
Field of Research
Cancer
Purity
99.55
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
COC1=CC=C(CCNCC2=C3C=CC=CC3=C(OC)C=C2)C=C1
Molecular Formula
C21H23NO2
Molecular Weight
321.41
Precautions
H318, H410
References & Citations
[1]Tal Varsano, et al. Inhibition of Melanoma Growth by Small Molecules that Promote the Mitochondrial Localization of ATF2. Clin Cancer Res. 2013 May 15;19 (10) :2710-22.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-164524SBI-0640726
HY-122682-01SBI-993
HY-19560-01SBI-0640756
HY-111534-01SBI-115
HY-125880-01SBI-553
HY-124418-01SBI-477
HY-164795-01SBI-810
HY-165245-01SBI-183
HY-16966-01SBI-0206965
HY-124756-01SBI-425

Alternative Products

CatalogName
T204265-01SBI-0087702
217553Mitochondrial ATF Translocator, SBI-0087702 (N- ((4-methoxynaphthalen-1-yl) methyl) -2- (4-methoxyphenyl) ethanamine, SBI0087702, SBI 0087702)
BA5337-5SBI-115
A8715-25SBI-0206965
BA8093-10SBI-425
BA3622-100SBI-0640756
BA8042-5.1SBI-797812
BA5627-100SBI-553
T89836-01SBI-0640726
BUP08927-01SBI-477

Popular Products