EP3 antagonist 2

• Description:

  EP3 antagonist 2 (Compound Exp 1) is a potent and selective EP3 receptor antagonist. EP3 antagonist 2 has a strong binding affinity for the human EP3 receptor (Ki: 3.3 nM) and significant antagonistic activity (IC50: 30.8 nM, determined by cellular cAMP levels) [1].

• UNSPSC:

  12352005

• Target:

  Prostaglandin Receptor

• Related Pathways:

  GPCR/G Protein

• Field of Research:

  Others

• Smiles:

  O=C1C([C@]2(C)C(NCCC2)=O)=CC=C(C3=CC4=C(C)C=CC=C4N=C3)N1

• Molecular Formula:

  C21H21N3O2

• Molecular Weight:

  347.41

• References & Citations:

  [1]Kevin Bahnck, et al. Antagonists of prostaglandin ep3 receptor. US20160176851A1. 2016-06-23.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1952261-87-8]