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EP3 antagonist 5

CAT: 0804-HY-157494Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-157494Size:1 Each
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Description
EP3 antagonist 5 (Compound 22) is an EP3 receptor antagonist with an IC50 value of 67 nM[1].
CAS Number
499147-44-3
UNSPSC
12352005
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ep3-antagonist-5.html
Solubility
10 mM in DMSO
Smiles
O=C(O)CCC1=CC=C(C=C1C(NC(C2=CC=C(C(F)=C2)C)CC(C)C)=O)COC3=CC=CC=C3
Molecular Formula
C29H32FNO4
Molecular Weight
477.57
References & Citations
[1]Asada M, et al. 3- (2-Aminocarbonylphenyl) propanoic acid analogs as potent and selective EP3 receptor antagonists. Part 2: Optimization of the side chains to improve in vitro and in vivo potencies[J]. Bioorganic & medicinal chemistry, 2010, 18 (4) : 1641-1658.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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