ML 086

• Description :

  ML 086 is a highly selective PHOSPHO1 phosphatase inhibitor (IC50=0.14 μM) . ML 086 is promising for research of hereditary vascular calcification disorders (e.g., generalized arterial calcification of infancy) and spinal ligament ossification[1].

• UNSPSC :

  12352005

• Target :

  Phosphatase

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Cardiovascular Disease

• Smiles :

  O=C(N(C)C)C1=CC=CC(N2SC3=C(C=CC=C3)C2=O)=C1

• Molecular Formula :

  C16H14N2O2S

• Molecular Weight :

  298.36

• References & Citations :

  [1]Bravo Y, et al. Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1. Bioorg Med Chem Lett. 2014 Sep 1;24 (17) :4308-11.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1177148-36-5]