SB-699393

• Description :

  B-699393 (Compound 17) is a BRAF inhibitor (Kd = 7.2 nM) that can cross the blood-brain barrier. SB-699393 can be used for research on stroke[1].

• UNSPSC :

  12352005

• Target :

  Raf

• Related Pathways :

  MAPK/ERK Pathway

• Field of Research :

  Cardiovascular Disease

• Smiles :

  O/N=C1C2=CC=C(C3=C(C4=CC=NC=C4)OC(CN5CCOCC5)=C3)C=C2CC/1

• Molecular Formula :

  C23H23N3O3

• Molecular Weight :

  389.45

• References & Citations :

  [1]Takle AK, et al. The identification of potent, selective and CNS penetrant furan-based inhibitors of B-Raf kinase. Bioorg Med Chem Lett. 2008 Aug 1;18 (15) :4373-6.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [502638-39-3]