SC-44463

• Description:

  SC-44463 is a synthetic collagenase inhibitor. SC-44463 can inhibit tumor cells invasion. SC-44463 can block ovulation, inhibit action of ovarian interstitial collagenase, and inhibit action of the small metalloproteinase of the rat uterus. SC-44463 can be used for the researches of cancer and endocrinology[1][2].

• UNSPSC:

  12352005

• Target:

  MMP

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Cancer; Endocrinology

• Smiles:

  O=C([C@@H](CC(NO)=O)CC(C)C)N[C@H](C(NC)=O)CC1=CC=C(C=C1)OC

• Molecular Formula:

  C19H29N3O5

• Molecular Weight:

  379.45

• References & Citations:

  [1]Axelrod JH, et al. Expression of human recombinant plasminogen activators enhances invasion and experimental metastasis of H-ras-transformed NIH 3T3 cells. Mol Cell Biol. 1989 May;9 (5) :2133-41.|[2]Butler TA, et al. Inhibition of ovulation in the perfused rat ovary by the synthetic collagenase inhibitor SC 44463. Biol Reprod. 1991 Jun;44 (6) :1183-8.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [104408-38-0]