BMS-694153

• Description:

  BMS-694153 is a potent antagonist of the human calcitonin gene-related peptide receptor (CGRP Receptor) . BMS-694153 can be used for migraine with rapid and efficient intranasal exposure[1].

• UNSPSC:

  12352005

• Target:

  CGRP Receptor

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Field of Research:

  Neurological Disease

• Smiles:

  O=C1N (C2CCN (CC2) C (N[C@@H] (C (N3CCC (N4CCCCC4) CC3) =O) CC5=CC (C) =C (NN=C6) C6=C5) =O) CC7=CC=CC (F) =C7N1

• Molecular Formula:

  C35H45FN8O3

• Molecular Weight:

  644.78

• References & Citations:

  [1]Degnan AP, et al. Discovery of (R) -4- (8-fluoro-2-oxo-1,2-dihydroquinazolin-3 (4H) -yl) -N- (3- (7-methyl-1H-indazol-5-yl) -1-oxo-1- (4- (piperidin-1-yl) piperidin-1-yl) propan-2-yl) piperidine-1-carboxamide (BMS-694153) : a potent antagonist of the human calcitonin gene-related peptide receptor for migraine with rapid and efficient intranasal exposure. J Med Chem. 2008 Aug 28;51 (16) :4858-61.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  1050381-35-5