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AR-12463

CAT: 0804-HY-113526Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-113526Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AR-12463 is a derivative of Trapidil. AR-12463 inhibits the conversion of [14C]acetate to cholesterol. AR-12463 significantly reduces the elevation of total cholesterol in rabbit serum and prevents cholesterol incorporation into tissues. AR-12463 can be used to study atherosclerosis.
CAS Number
100557-04-8
UNSPSC
12352005
Target
Drug Derivative; Endogenous Metabolite
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cardiovascular Disease
Smiles
OCCN(CCCCC)C1=CC(N2CCCCC2)=NC3=NC=NN31
Molecular Formula
C17H28N6O
Molecular Weight
332.44
References & Citations
[1]Beitz J, et al. Influence of the trapidil derivative AR 12463 on serum and tissue lipids and development of aortic lesions during experimental atherosclerosis in rabbits. Biomed Biochim Acta. 1991;50 (1) :101-7. PMID: 1859385.|[2]Beitz J, et al. Influence of the trapidil derivative AR 12463 on serum and tissue lipids and development of aortic lesions during experimental atherosclerosis in rabbits. Biomed Biochim Acta. 1991;50 (1) :101-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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